GOS Bio-active is an important dietary fiber.
Boost your child's immunity and promote easy bowel movements.

Many mothers may wonder why their children get sick easily and have to go to the hospital frequently, while some children are healthier or get sick less often than their peers. This is because each child's immune system is different, and their immune levels vary at different ages. The development of the immune system is progressive and becomes more complex from birth to adulthood. ^[1]

The most common immune system problems in young children aged 1-3 years are as follows:

Respiratory infections are common. Children this age often catch colds or respiratory infections because their immune systems are not yet able to fight off germs effectively. ^[2]
Gastrointestinal infections: Children's gut immune systems are not yet strong, making them susceptible to gastrointestinal infections such as diarrhea ^[2].
Incomplete vaccine response is due to the underdeveloped immune system. Post-vaccination immunity may be incomplete, requiring scheduled booster shots ^[2].
An overreaction to foreign substances: A child's immune system may react to seemingly harmless foreign substances, such as dust or certain foods, causing allergies or intolerances. ^[2]
Bowel movements: If constipated, hard stools can lead to the buildup of harmful bacteria in the gut, resulting in inflammation and reduced immune function. These problems not only affect a child's comfort but can also impact their nutrient absorption and overall growth. ^[3]

Nutrients that help boost immunity in young children aged 1-4 years.

Vitamin C helps stimulate the function of white blood cells such as neutrophils and lymphocytes, which play an important role in preventing infection and strengthening the mucous membranes that protect the body from external pathogens. A deficiency in vitamin C can weaken the immune system and increase the risk of infection ^[2] . Getting enough vitamin C helps maintain the normal functioning of the immune system.
Vitamin E helps strengthen the immune system as vitamin E is an antioxidant, prevents cell degeneration and stimulates the function of white blood cells which help fight off germs and prevent autoimmune disease ^[3].
GOS Bio-active helps boost immunity by promoting the growth of beneficial bacteria in the gut, strengthening the immune system, reducing the risk of infections and promoting digestive health ^[4].

What is GOS Bio-active and why is it important?

GOS Bio-active (Galacto-oligosaccharides – Biological Active Ingredients) is a prebiotic, a dietary fiber with unique properties, a food source for good gut bacteria, helping to balance the digestive system and boost the immunity of your baby ^[5] , leading to better health and reducing the risk of illness ^[6,7]. Because GOS Bio-active has the special property of not being broken down in the stomach and small intestine, it can travel directly to the large intestine. GOS Bio-active acts as food for good gut bacteria, especially Bifidobacteria and Lactobacillus ^[6]. Therefore, when mothers choose UHT milk products containing GOS Bio-active, it will help their babies be ready to face the outside environment with confidence and safety.

Research supports that GOS Bio-active helps with the digestive system and strengthens the immune system of young children.

Research in children has shown that supplementing infant formula with prebiotics can reduce constipation and increase secretory IgA, which helps prevent urinary tract infections ^[3]. Experimental results indicate that consuming approximately 5-6 grams of GOS Bio-active per day, continuously for at least 3 weeks, can have a noticeable effect. Consuming approximately 5.5 grams of GOS Bio-active per day for 10 weeks can increase the level of gut bifidobacteria, resulting in increased levels of IL 10 (anti-inflammatory cytokine) and decreased levels of IL 1β, a signal of inflammation. This research demonstrates the positive effects of consuming GOS Bio-active ^[4].

Because young children's immune systems are not yet fully developed, they need a protective shield to boost their immunity. This includes vaccinations, immune boosters, sufficient sleep, a balanced diet with all five food groups, and choosing UHT milk fortified with Vitamin C and GOS Bio-active. This helps support immunity in three ways: 1. Improves digestive balance and nutrient absorption. 2. Boosts immunity because GOS Bio-active stimulates the production of antibodies, which help protect against pathogens entering the body. 3. Reduces inflammation in the body, making your child's immune system strong and ready to fight off diseases effectively.

In summary , we cannot deny that taking children to explore the world helps foster their development and growth. However, parents must also prepare to prevent or reduce the risk of illness. Choosing UHT milk fortified with GOS Bio-active and other essential nutrients such as DHA, Omega 3, 6, and 9, Vitamin B12, Vitamin C, and calcium is a crucial aid. It not only supports physical development and immunity but also promotes healthy brain development, preparing children to confidently face any challenges from the external environment.

Dr. Siriporn
Wongwaree family

Written by:

Pediatric Allergist and Immunologist
Kasemrad International Hospital, Rattanathibet

Dr. Siriporn
Wongwaree family

Pediatric Allergy Specialist
and immunity.
Kasemrad Hospital
International Rattanathibet

Written by:

Dr. Siriporn
Wongwaree family

Neonatal and Immunology Pediatrician
Kasemrad International Hospital, Rattanathibet

Frequently Asked Questions

What is GOS Bio-active?

Galacto-oligosaccharide (GOS) prebiotics have unique properties and serve as "food" for beneficial microorganisms in the intestines.
Helps to maintain a balanced and optimal microbiome.

In what ways does GOS Bio-active benefit the body?

Supports the digestive and excretory systems by increasing bifidobacteria/lactobacillus in the intestines.
Boosts immunity by stimulating the production of secretory IgA, which helps prevent coronavirus from entering the body.
Supports the overall well-being of children when consumed continuously in appropriate amounts.

Can GOS Bio-active help with constipation?

There is evidence that continued supplementation with GOS bio-active helps reduce constipation and increases beneficial bacteria associated with more comfortable bowel movements.

reference

1. Abbas AK, Lichtman AH, Pillai S. Basic immunology: functions and disorders of the immune system. 5th ed. Philadelphia: Elsevier; 2024.

2. Chutawan Nuanchankong, Faculty. The role of nutrition on the immune system. Journal of Research and Innovation in Science and Technology. 2022;3(4):19-30.

3. Sela DA, et al. Prebiotics in infant nutrition. J Pediatr Gastroenterol Nutr. 2008;47(4):375–380.

4. Vulevic J, et al. Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. Am J Clin Nutr. 2008;88:1438–1446.

5. Sierra C, Bernal MJ, Blasco J, Martínez R, Dalmau J, Ortuño I, Espinosa J. Prebiotic effect during the first year of life in healthy infants fed formula containing GOS as the only prebiotic: a multicentre, randomized, double-blind and placebo-controlled trial. Eur J Nutr. 2015 Feb;54(1):89–99. doi:10.1007/s00394-014-0689-9.

6. Schley PD, Field CJ. The immune-enhancing effects of dietary fibers and prebiotics. Br J Nutr. 2002;87(S2):S221–S230.

7. Arslanoglu S, Moro GE, Boehm G. Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr. 2007 Nov;137(11):2420–4. doi:10.1093/jn/137.11.2420.